Diabetes in Birds

Diabetic Cockatiel
Diabetic Cockatiel

Diabetes Mellitus In Birds

"Has my bird really got diabetes??? Doc you must be joking???  Why does a bird get diabetes???"

Charlie was an 8-year-old male lutino cockatiel weighing 78.9 grams. He was a well loved pet that enjoyed freedom allowed out of his cage every day.  He had a gutsy personality – and his owners told me how fussy Charlie was with his food. He refused everything except for his “nice” seed mix. That was the only thing he ate over the last few years. He presented at Highbury Veterinary clinic for assessment.

The following clinical signs typical of Diabetes were seen:

  • Excessive thirst – called polydipsia. We measured his water consumption and found that Charlie drank more than half his body weight daily, about 55 ml of water a day. This is about 7 times more than normal.
  • Excessive urine production – called polyuria. A bird passes droppings consisting of three separate entities – Firstly stool from the intestines -secondly urine from the kidneys – and lastly uric acid from the chalky white part also from the kidneys. There were large volumes of urine forming small puddles under his favourite perch.
  • Excessive eating – called polyphagia – compared to the other cockatiel cage mate he was eating more than normal.
  • Weight loss – over the last few weeks Charlie had gradually lost weight – even though he was eating well.
  • Occasional bouts of sleepiness that had become more noticeable over the last few weeks.

The owner was informed of the necessity to diagnose the condition, and the various diagnostics testing available that would help us to manage the case. We elected to do laboratory blood testing – both haematology and biochemistry panel, urine testing and body radiographs and chlamydophilia testing.

But doc how do you take blood from my bird? How much blood will you take?  Will my bird survive the procedure?” Charlie’s concerned owner asked.

We took 0.14 millilites of blood (about 1 tenth of 1 ml). The bird tolerated the procedure well.  Blood is usually taken from the right jugular.

The abnormal tests results were repeated twice the next day, both tests results showed high glucose in both the blood and urine. It was important to repeat the tests, as a single elevated blood glucose sample is not diagnostic. The diagnosis was confirmed as Diabetes Mellitus.

The blood results confirmed our suspicions that the blood glucose was high - much higher than normal and the liver enzymes were also elevated.

The urine was analysed and found to contain lots of glucose.

What is the cause of diabetes in birds?

 

Parrots have unique evolutionary adaptations. They have blood glucose levels about three times as high as mammals. Three hormones act together to maintain the high blood glucose level. The glucose lowering effects of insulin are much less important in birds than in mammals. The disease is caused only partly by an inulin deficiency.  Often the glucose elevating hormones are also raised making therapy more challenging.

 

Parrots fed on an all seed diet are predisposed to metabolic diseases. Most readers will be aware of the vitamin A and calcium deficiency that is associated with all seed diets.  In total 32 nutrients are lacking from the commonly fed seeds like oats, corn, sunflower, safflower and millet. The excess fat content and low nutrient content may results in all of the following to some extent: obesity, thyroid disease, fatty liver, renal disease, skin and feather disorders, pancreatic disease gastro intestinal disease and Diabetes mellitus.  The diseases listed are all somewhat interrelated.

In Charlie’s case, we suspected that major contributing factors were underlying poor nutrition, liver disease and pancreatic disease.

Treatments for Diabetes in Birds:

 

There are three main treatments all resulting in a lowering of blood glucose and then a decrease in clinical signs.

 

  • Oral glucose lowering drugs – The medication is added to the water and so the more the bird drinks the more it gets. The patient self regulates the dose. As the polydipsia resolves the amount of drug ingested decreases.
  • Dietary therapy – to a complete formulated diet to replace the seeds. These diets are much lower in fat compared to seeds. They are also balanced in nutrients. This is often the most important part of the therapy.
  • Insulin injections to help stabilise the patient. As Bird insulin is not commercially available we use mammalian insulin. It needs to be diluted which further affects its potency. It is different from mammalian inulin and there may be a reaction to it. So we only use insulin in birds when the glucose level does not normalise with diet and in water medications. Injecting insulin daily is often not practical or an option for many owners. Chicken insulin has been made, and it may be a better alternative.

 

These are generally treatments rather than cures, and used to stabilise our patients while the metabolic disease is corrected. Many birds respond so well to treatments 1 and 2 above that they often go into remission and require no further therapy.

5 Comments

  1. Linda Vitelli on July 25, 2023 at 8:09 am

    Thank you for posting this video. My Yellow Nape Amazon parrot who is 40 years old was recently diagnosed with diabetes and there is not much information out there for this especially regarding diet. Her glucose level was 700. The Vet put her on glipizide to be taken on a small piece of food but one month into the dosing and I have not seen much improvement in her polyuria. Her diet has never been seed. I feed her Zupreem Natural Pellets and vegetables so I am certainly shocked that she has such a disease! Today my Vet told me to put her on a Paleo diet and to research what Amazons eat in the wild and base what I feed her on that. I hope that works… TY for the information

    • Eithan Giles on July 27, 2023 at 9:21 am

      Hi Linda, thank you for watching our video and reading our article. If you would like more information and to speak to one of our avian vets you can book online with us, we can do international consultations via zoom / phone call just take in mind that our timezone is AEST. Kind regards, Eithan. Senior Veterinary Nurse

    • Kendall Osborne on September 6, 2023 at 3:04 pm

      Unfortunately ZuPreem is a lower quality pellet of which its main ingredient is ground corn and soybean meal. A cold pressed vegetable based pellet is actually closer to the healthy diet in the wild, but the best diet is fresh vegetable chop and sprouts. The pet food companies certainly sold us all a bill of good by getting us all to believe that their pellets were the preferred diet, and more and more birds are developing these health problems as a result. Im sorry that happened to you.

    • Margaret Bjelica on January 15, 2024 at 3:44 am

      I have my toucan on Prozinc NPH insulin twice daily. He is doing great, but each diagnosis is different.

  2. Candice on January 12, 2024 at 4:14 am

    Hi! I’m in South Africa and my ring neck alexandrine part who is 22 years old has high glucose in her irons. Unfortunately glipizide has been discontinued in South Africa. Would gliclazide work the same way? Thanks so muc!

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